|
KMID : 0931320120120020075
|
|
대한상부위장관.헬리코박터학회지
2012 Volume.12 No. 2 p.75 ~ p.81
|
|
|
Molecular Biology of Upper Gastrointestinal Neoplasms
|
|
Kim Joon-Sung
Kim Byung-Wook
|
|
|
Abstract
|
|
|
|
Neoplasms of the upper gastrointestinal tract are related by location and have distinct clinical and molecular characteristics. Malignancies of the upper gastrointestinal tract are often diagnosed at an advanced stage and are generally associated with a poor patient prognosis. Improved understanding of the molecular biology of these tumors should provide new targets for diagnosis, chemoprevention, and therapy. This review focuses on the molecular biology of esophageal adenocarcinoma, esophageal squamous cell carcinoma and gastric adenocarcinoma. Fundamental principles of carcinogenesis are discussed first, followed by the key similarities and differences of each cancer.
|
|
|
KEYWORD
|
|
|
Neoplasms, Upper gastrointestinal tract, Molecular biology
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|